Research & Trials
Full-scope cardiovascular research.
CRI is a full-scope cardiovascular research organization: a trial site for sponsors, a full-service CRO, and a developer of original diagnostics, all under one roof.
By the Numbers
12+
Studies Conducted
1,500+
Patients Enrolled
7
Active Sponsors
~2 weeks
Avg. Site Activation
15+
Publications & Abstracts
Figures reflect combined site and investigator experience; study count is approximate pending final confirmation.
Track Record
Selected trials & validation work
Sponsor & Investigator Trials
Prospective, international, sham-controlled, randomized, patient- and assessor-blinded trial of alcohol-mediated renal denervation for Ablative Solutions (2019–2022). Primary results published in Circulation.
NCT02910414on ClinicalTrials.govPhase 3 trial evaluating abelacimab in high-risk patients with atrial fibrillation deemed unsuitable for current anticoagulants. Active.
NCT05712200on ClinicalTrials.govFingertip and wrist cuffless blood-pressure validation in older adults (2023); large-scale biometric studies across hypertensive and hypotensive populations.
Enhanced external counterpulsation research spanning blood pressure, heart rate, and heart failure — including a 2025 NASA Human Research Program workshop selection on post-spaceflight reconditioning.
Virtual-reality cognitive behavioral therapy for stage 1–2 hypertension in outpatient cardiology (2022–2023).
Additional current sponsor work across cardiovascular therapeutics, devices, and AI, disclosed as each study becomes public.
Device, Diagnostic & AI Validation
Automated external defibrillator validation supporting FDA approval.
Cairdio/Lightscope heart-murmur detection, Ainthoven AI ECG analysis, and Cloud Stream medical-imaging echo platforms.
Student-athlete ECG screening with the Cody Stephens Foundation, supporting Texas House Bill 76 (the Cody Stephens Bill).
Sponsor Services
Six ways to work with CRI
Every engagement follows the same four-part structure: overview, what's included, deliverables, and an indicative timeline. Timelines are ranges, never fixed commitments.
Sponsor Trials
A ready cardiovascular site for pharmaceutical and device trials across all phases.
Full-Service CRO
End-to-end support for sponsors and investigators running their own protocols. All functions in-house.
Device & Diagnostic Validation
Independent clinical validation of cardiovascular devices and diagnostics against regulatory-grade endpoints.
AI & Digital Health
Real-world validation of AI algorithms, remote monitoring, and digital health platforms.
Internal IP & Investigator-Initiated Research
Original research and technology developed in-house, from concept to publication.
Regulatory, Quality & Biostatistics
The compliance and analytics backbone supporting every study.
Site & Infrastructure
A research suite inside a working cardiology practice
CRI operates inside a working cardiology practice, Houston Cardiology Consultants (HCC), directly connected to our Principal Investigator. The front of the facility is an active clinical cardiology office; the back is a dedicated, separate research suite. That integration gives us a built-in cardiovascular patient population and direct, physician-led referral into trials, while keeping clinical care and research operations physically distinct.
Diagnostic Cardiology (Non-Invasive)
8 capabilities
Vascular & Preventive
7 capabilities
Interventional Cardiology
1 capability
Electrophysiology
2 capabilities
Lab & Specimen Handling
5 capabilities
Research Infrastructure
11 capabilities
Data, IT & Remote Monitoring
6 capabilities
Staff Certifications
9 capabilities
Facility Gallery
A look inside the Houston site — clinic, research suite, and meeting rooms.
Clinic reception (HCC)
Patient exam / consult room
Research suite
Boardroom / conference room
Standards & Innovation
Innovation & internal IP
Innovation & Internal IP
Beyond sponsor and CRO work, CRI conducts its own investigator-initiated research: small, in-house projects that test new questions in cardiovascular care, AI, and digital health. This work is published in peer-reviewed journals and presented at national meetings, including the American Heart Association's Scientific Sessions. It's how we stay at the edge of the field and bring that rigor back to the partners we work with.
Applied AI Case Studies
Partners & Sponsors
The teams we help bring cardiovascular innovation to life.
From emerging medtech to established sponsors, we partner with the companies and institutions turning new ideas into validated, real-world care.
Names reflect trial sponsors and study partners CRI has worked with. Logos appear for brands already featured on Lone Star Summit; remaining partners stay as text until permissioned.